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Huberman Lab Intro

0:09 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

Huberman Lab
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Andrew Huberman Intro

2:20 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Andrew's Disclaimer

0:16 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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1:18 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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1:08 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Ketamine Is Similar to PCP; Despite Clinical Use Cases, Addiction Is Possible

3:48 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Antidepressant Drugs That Increase Monoamines Only Reduce Symptoms in 40% of People

3:29 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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As a Dissociative Anesthetic, Ketamine Is Often Used to Induce Certain Forms of Anesthesia

2:46 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Mice Injected With Ketamine Swim for Their Life a Lot Longer Before Giving Up

6:53 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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IV Ketamine (0.5 mg Per kg of Body Weight) Rapidly Reduces Depressive Symptoms

6:21 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Taking Ketamine 2x/Week for 3 Weeks Relieves Depressive Symptoms for Months

4:53 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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1:04 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Ketamine Blocks the NMDA Receptor, Which Is Crucial for Many Forms of Neuroplasticity

7:07 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Ketamine Binds to NMDA Receptors on Inhibitory Neurons, Increasing Excitatory Neuron Activity

6:49 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Ketamine Increases Neuroplasticity By Dampening Inhibitory Neuron Activity

5:08 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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The NMDA Receptor Blockade Explains Ketamine Therapy's Longer Term Effects

2:00 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Ketamine Relieves Depression By Stimulating BDNF Release & Mimicking the Molecule Itself

5:23 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Unlike Psilocybin, Multiple Mechanisms Contribute to Ketamine's Antidepressive Effects

1:29 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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1:12 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Ketamine Binds to Various Opioid Receptors, Leading Many People to Use It Recreationally

4:21 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Ketamine's Antidepressant Effects Are Nonexistent When Opioid Receptors Are Blocked

2:49 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Andrew Huberman Views Ketamine's Antidepressant Effects as a Wavefront

4:54 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Ketamine Therapy Increases Dopamine Reward Pathway Availability Via Habenula Suppression

4:50 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Ketamine Strengthens Neural Connections Related to Context-Dependent Strategy Building

2:09 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Andrew Huberman Explains What Causes Ketamine's Profound Dissociative Effects

3:35 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Typical Ketamine Doses Differ Based on Delivery Mode: IV vs. Oral vs. Sublingual

2:35 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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K-Holes Are When People Take Ketamine & End Up in a Pseudo-Anesthetized State

3:28 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Ketamine Is Sometimes Taken Rectally to Minimize Liver Damage

1:17 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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The Most Effective Forms of Ketamine for Treating Depression: S/R > S > R

3:29 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Zero Evidence Suggests Microdosing Ketamine Treats Depression

1:12 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Andrew Huberman Outro (Part I)

2:19 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Support the 'Huberman Lab' Podcast

0:30 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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0:23 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Connect With Andrew Online

0:20 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Subscribe to Andrew's Neural Network Newsletter

0:31 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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Andrew Huberman Outro (Part II)

0:11 · Ketamine: Benefits and Risks for Depression, PTSD & Neuroplasticity - Andrew Hubermanview episode

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