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Psilocybin mainly binds to and activates the so-called serotonin 2A receptor ... Serotonin 2A is expressed in particular areas of the brain—and even on particular areas of neurons in the brain—that allow for very specific types of changes in neural circuitry to take place, not just when one is under the influence of psilocybin but afterwards as
well.
Andrew Huberman
Psilocybin Binds to the Serotonin 2A Receptor, Triggering Therapeutic Benefits
How Psilocybin Can Rewire Our Brain, Its Therapeutic Benefits & Its Risks
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