AMA #38: Can you exercise too much?

Whether it be ASCVD, cancer, type 2 diabetes, Alzheimer's disease, all-cause mortality, it doesn't matter—exercise is going to reduce the toll of mortality across all of those things.

1 MET is the energy cost of being alive at rest ... Worth noting that 1 MET is equivalent to 3.5 mL per minute per kg of oxygen utilization ... If you are doing 10 METs of exercise, you are consuming 35 mL of oxygen per minute.